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Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy

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Hoveidaei 2 1 School of Medicine, Tehran Univ

Cleavage under targets and tagmentation sequencing (CUT&Tag-seq), chromatin immunoprecipitation with quantitative PCR (ChIPqPCR), and ChIPre-ChIP analyses all revealed the enrichment of H1(N76D/N77D) at the 80 sensitive damaged sites prone to both homologous recombination and non-homologous end-joining (NHEJ) repair pathways (Fig